β‐Adrenergic Stimulation Increases Protein Secretion But Not Fluid Flow in Mouse Lacrimal Gland
نویسندگان
چکیده
منابع مشابه
Protein in rabbit lacrimal gland fluid.
A variety of proteins have been identified in tears, which are composed of secretions from all the orbital glands. It has been assumed that the lacrimal gland was the source of these proteins because there is indirect evidence that the lacrimal gland can secrete protein in response to cholinergic stimulation. In the present study, the concentration of protein was determined in lacrimal gland fl...
متن کاملFluid secretion and the Na+-K+-2Cl- cotransporter in mouse exorbital lacrimal gland.
We have previously suggested that fluid flow in the mouse exorbital lacrimal gland is driven by the opening of apical Cl- and K+ channels. These ions move into the lumen of the gland and water follows by osmosis. In many tissues, the Na+-K+-2Cl- cotransporter (NKCC1) replaces the Cl- and K+ ions that move into the lumen. We hypothesize that mouse exorbital lacrimal glands would have NKCC1 co-tr...
متن کاملChanges in rabbit lacrimal gland fluid osmolarity with flow rate.
To determine whether the osmolarity of rabbit lacrimal gland fluid (LGF) changes with flow rate, microvolumes (approximately 0.2 microliters) were collected directly from he cannulated glandular excretory duct of anesthetized rabbits. Low flow rates were obtained by collection of LGF 5 min after instillation of proparacaine: higher flow rates were obtained by stimulation with 0.45, 0.9, 3.8, or...
متن کاملSialic acid in rabbit lacrimal gland fluid.
To date, there has been no attempt to determine which of the orbital glands contribute the sialic acid, which has been found in tears and tear mucoids. In the present study, sialic acid was found in the fluid collected directly from the lacrimal gland excretory duct, uncontaminated by the secretions of the other orbital glands (Nictitans, Harderian, conjunctival) as well as in the fluid secrete...
متن کاملRetinol secretion by the lacrimal gland.
In order to determine the source of the retinol which has been identified in the tear fluid, the lacrimal gland ducts of rabbits and rats were cannulated and the collected lacrimal gland fluid was analyzed by high performance liquid chromatography. Retinol was identified in the lacrimal gland fluid of rabbits and rats, and it is concluded that the lacrimal gland is the source of retinol in the ...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2006
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.20.5.a836-d